Fertility & Pregnancy8 min read

PCOS and Ovulation: Improving Fertility Outcomes

A deep dive into how PCOS affects ovulation, diagnostic markers, and interventions that improve chances of conception.

What You'll Learn

  • How PCOS disrupts ovulation
  • Diagnostic signs of anovulation
  • Medical and lifestyle approaches to induce ovulation
  • How ovulation tracking can assist conception

PCOS and Its Impact on Ovulation

Polycystic Ovary Syndrome (PCOS) is one of the leading causes of anovulatory infertility. The condition disrupts the hypothalamic-pituitary-ovarian (HPO) axis, leading to irregular or absent ovulation. Elevated luteinizing hormone (LH) levels and hyperandrogenism impair follicular maturation, often causing multiple immature follicles to develop without a dominant follicle reaching ovulation.

Key Fertility Stats in PCOS

70–80%

PCOS patients experiencing ovulatory dysfunction

50–60%

Women with PCOS who are overweight or obese

70%

Improvement in ovulation rate with lifestyle changes

Diagnosing Anovulation

Irregular menstrual cycles (typically >35 days), absence of cervical mucus changes, and lack of mid-cycle LH surge are clinical indicators. Ultrasound often shows a 'string of pearls' pattern on ovaries, and serum progesterone <3 ng/mL in the luteal phase confirms anovulation.

Interventions to Promote Ovulation

Several first-line and adjunctive therapies are used to trigger ovulation:

Diagnostic Process

1

Weight loss of 5–10% in overweight women can restore spontaneous ovulation

2

Clomiphene Citrate or Letrozole are commonly prescribed ovulation inducers

3

Metformin improves insulin sensitivity, indirectly restoring ovulation in some cases

4

Gonadotropin therapy may be considered in resistant cases under specialist supervision

Tracking and Supporting Ovulation

In addition to medical support, fertility-focused individuals with PCOS benefit from monitoring their ovulation through:

Monitoring Tools

  • Basal Body Temperature (BBT) charting
  • Ovulation Predictor Kits (OPKs) — though LH surges may be unreliable in PCOS
  • Mid-cycle transvaginal ultrasound
  • Serum progesterone levels post-ovulation

Lifestyle Support

  • Low-glycemic diet to stabilize insulin and hormones
  • Moderate-intensity exercise like brisk walking or swimming
  • Stress-reduction practices like mindfulness and yoga
  • Adequate sleep and circadian rhythm alignment

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Take Control of Your PCOS Journey

Download Aora to track symptoms, monitor cycles, and get personalized insights