Treatment Options9 min read

Supplements: Myo-Inositol, Omega‑3, and Vitamin D

Comprehensive review of evidence-based supplements—Myo‑Inositol, Omega‑3 fatty acids, and Vitamin D—for metabolic, reproductive, and mood support.

What You'll Learn

Benefits and mechanisms of key supplements
Clinical dosage evidence and outcomes
Organized usage alongside medications
Safety considerations and contraindications

Myo‑Inositol

This natural insulin sensitizer improves ovulatory function and metabolic profile. Trials report ~75–80% ovulation restoration in young PCOS women using 2–4 g/day.

Omega‑3 Fatty Acids

EPA/DHA supplements (2–3 g/day) reduce inflammation, improve lipid profiles, and may support insulin sensitivity in PCOS.

Vitamin D

Deficiency is common in PCOS and correlates with insulin resistance and mood issues. Supplementation to maintain serum levels of 30–50 ng/mL is advised.

Supplement Outcomes

75%

Ovulation improvement with Myo-Inositol

15–25%

Reduction in triglycerides with Omega‑3s

30%

Improvement in insulin resistance with Vitamin D correction

Using Supplements Safely

Under medical guidance, consider:

Diagnostic Process

Start Myo-Inositol 2g BID with food

Take Omega‑3s (EPA + DHA) 2g/day with meals

Supplement Vitamin D based on serum levels (usually 1,000–2,000 IU/day)

Combine supplements with medications only under supervision

Benefits & Safety

These can:

Support ovulation

Aid menstrual regularity and fertility

Reduce inflammation

Lower CRP and triglycerides

Interact with drugs

Inform your doctor about all supplements

Medical Disclaimer

⚠️ Supplements should be used **only after consulting with your healthcare provider**, especially if taking prescription medications.

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